Procaccini established a reputation as a leading painter in Milan, having first trained and worked as a sculptor. He was born in Bologna but moved to Milan as a boy with his family. His father and elder brothers were also painters. Procaccini's dramatic religious paintings include daring foreshortening and numerous figures. Their solid forms relate to his experience of sculptural projects. He was also influenced by Rubens, whom he met while working in Genoa, and the effect of this is evident in his later work for the Savoy court in Turin.