This elaborate triptych centres around the scene of the Deposition. The drapery and costumes are sumptuous, as was customary for Antwerp paintings of this period. Behind the main scene, the landscape recedes far into the distance. The donors appear in the wings, accompanied by their patrons saints, St John the Baptist and St Margaret of Antioch.They have been identified as Jan Perls, burgomaster of Antwerp, and his wife, Digna de Herde, on the basis of the coats of arms included at the top of the wing panels.